[J61441] CAS 144701-48-4 | Telmisartan, 98%
0 ₩
144701-48-4 |
CAS : 144701-48-4
MDL : MFCD00918125
Other name :
BIBR 2774′-[(1,4′-Dimethyl-2′-n-propyl[2,6′-bi-1H-benzimidazol]-1′-yl)methyl]biphenyl-2-carboxylic acid
Chemical Properties
Formula : C33H30N4O2
Formula weight : 514.62
Melting Point : 261-263°
Sensitivity : Ambient temperatures.
Form : Powder
Solubility : Soluble in DMSO (13 mg/ml at 25°C), chloroform, DMF (~1.6 mg/ml), and ethanol (<1 mg/ml at 25°C). Insoluble in water.
Applications
Telmisartan also acts as a partial agonist of PPARγ, activating the receptor to 25-30% of that produced by the full agonist rosiglitazone (EC50 = 4.5 ?M). Through these actions, telmisartan potently reduces blood pressure in various animal models of hypertension, diminishing cardiac hypertrophy, cardiovascular and renal risk, and glomerulosclerosis.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements :
Precautionary Statements :
Other References :
Merck : 14,9129
| Pakage | 1g, 250mg |
|---|---|
| brand | Alfa Aesar |
