[02101516-CF] CAS 9011-18-1 | Dextran sulfate sodium salt (8,000 (avg) Da) | MP bio
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Brand: MP Bio
- Polyanionic derivative of dextran with an average of 1.9 sulfate groups per glucosyl residue
- High purity and consistant quality enables its application in pharmaceuticals and biotechnology industry
- Can be used as an anticoagulant, antiviral and antilipemic agent
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02101516-CF | CAS 9011-18-1 | Dextran sulfate sodium salt (8,000 (avg) Da) | MPBIO
Key Features and Details
- Polyanionic derivative of dextran with an average of 1.9 sulfate groups per glucosyl residue
- High purity and consistant quality enables its application in pharmaceuticals and biotechnology industry
- Can be used as an anticoagulant, antiviral and antilipemic agent
| SKU | 02101516-CF |
| Alternate Names | Dextran sodium sulfate; DSS |
| Application Notes | Dextran Sulfate Sodium (DSS) which has proven to have versatile value in Biomedical/clinical research. DSS can be used as an anticoagulant, antiviral as well as antilipemic agent.Dextran sulfate sodium shows immunologically relevant activities: enhancement and suppression of humoral immunity, polyclonal activation of B-lymphocytes, stimulating even immature B cells, changes in thymocyte reactivity to lectins, enhancement/suppression of cell-mediated immune responses. Precipitates LDL and VLDL lipoproteins – in the presence of magnesium ions, dextran sulfate precipitates low-density lipoproteins from human serum leaving the high-density lipoproteins in the supernatant. Removal of lipoproteins by dextran sulfate precipitation may be useful in the purification of other materials such as beta 2 glycoprotein. Exhibits activity as an adjuvant.Antiviral and Antienzyme Activity – Baba et al., have shown in In Vitro studies that DSS inhibits the binding of various enveloped viruses including Human Immunodeficiency Virus (HIV), Herpes Virus (HSV) and Cytomegalovirus (CMV) to cells. Additionally, DSS has also shown to exhibit a potent inhibitory effect on many enzymes, for example hyaluronidase, adenylate cyclase, and amylase. Hofer at al., have shown that DSS induces bacterial translocation in HIV-infected humanized mice. |
| Base Catalog Number | 101516 |
| Boiling Point | 310 °C |
| CAS # | 9011-18-1 |
| Grade | Reagent Grade |
| Melting Point | 92 °C |
| Molecular Weight | 8000 (avg) Da |
| Optical Rotation | +75 ° to 105 ° |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| RTECS Number | HH9290000 |
| Solubility | >24.8 [ug/mL] |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| Vapor Pressure | 2.6X10-4 mm Hg at 25 deg C /Estimated/ |
