[02190057-CF] CAS 1405-41-0 | Gentamycin sulfate, USP Grade | MP bio
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02190057-CF | CAS 1405-41-0 | gentamycin sulfate, USPgrade | MPBIO
Key Features and Details
- Inhibits the growth of a wide variety of Gram-positive and Gram-negative microorganisms
- For use in cell culture applications at 5 ml/L
- Used as a selection agent (gentamicin-resistance gene) in molecular biology applications
| SKU | 02190057-CF |
| Alternate Names | Garamycin; Gentamicin sulfate salt; Gentiomycin C |
| Application Notes | Gentamycin sulpahte is used as a selection agent (gentamicin-resistance gene) in molecular biology applications.It is used to treat many types of bacterial infections, particularly those caused by Gram-negative organisms. |
| Base Catalog Number | 190057 |
| Biochemical Physiological Actions | Gentamicin causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site. The bactericidal effect of gentamicin on Pseudomonas aeruginosa is exerted by the binding of gentamicin to the outer membrane, where it displaces natural cations, destabilizes the membrane, and forms holes in the cell surface. Antimicrobial spectrum: Gram-negative bacteria, Staphylococcus aureus and other Gram-positive bacteria. |
| CAS # | 1405-41-0 |
| EC Number | 215-778-9 |
| Grade | USP |
| Hazard Statements | H317-H334 |
| Molecular Weight | 1488.8 g/mol |
| Optical Rotation | ≤1.0% |
| Particle Size | +107° to +121°(10 mg/mL, water) |
| pKa | 3.5 – 5.5(1 in 25, in water) |
| Preparation Method | P261-P280-P342 + P311 |
| RTECS Number | LY2625000 |
| Safety Symbol | ≤1.0% |
| Source | H2O: soluble 50 mg/mL |
| Storage | BIOCHEMICALS |
| Unit Definition | This product is recommended for use at 50 mg/L. |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
