[0219454405] CAS 25988-63-0 | Poly-l-lysine hydrobromide, 5 mg | MP bio
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0219454405 | CAS 25988-63-0 | Poly-l-lysine hydrobromide | MPBIO
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Key Features and Details
Poly-L-Lysine Hydrobromide
| SKU | 0219454405 |
| Alternate Names | PLL HBr |
| Application Notes | Poly-L-lysine typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. When adsorbed to the culture surface, poly-lysine increases the number of positively charged sites available for cell binding. Can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. Other uses for poly-lysine have been reported as follow: 1.Conjugation to methotrexate for increased drug transport. 2.Microencapsulation of islets. 3.Use in simple reproducible procedure for chromosomal preparations from a variety of tissues. 4.Immobilation of living cells in biocompatible semipermeable microcapsules. 5.Poly-L-Lysine In the preparation of polycationic beads. 6.Conjugation to albumin and horseradish peroxidase to enhance cellular uptake. |
| Base Catalog Number | 19454405 |
| CAS # | 25988-63-0 |
| Format | Powder |
| Grade | Cell Culture Grade, γ-irradiated |
| Molecular Formula | (C6H12N2O·HBr)n |
| Molecular Weight | >70,000 Da |
| Pack Size | 5 mg |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| Sterility | γ-Irradiated |
| Typical Working Concentration | Typically, the effective coating solution concentration for culture dishes will be 0.3 to 0.5% and for histology slides at 0.1%. Recommended as a cell culture substratum when using 0.5 mL of a 0.1 mg/mL solution to coat 25 cm2. Optimal conditions for attachment must be determined for each cell line and application. |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
