[02151319-CF] CAS 4781-83-3 | 2-Iminothiolane hydrochloride | MP bio
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Brand: MP Bio
2-Thiolanimine hydrochloride; 2IT; Dihydro-2(3H)-thiophenimine hydrochloride; Trauts reagent
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4781-83-3 | 02151319-CF | 2-Iminothiolane hydrochloride
관련 문서 다운로드 (MSDS, COA, SPEC, Datasheet, Brochures, Manuals) :
Key features and details
2-Iminothiolane Hydrochloride
| SKU | 02151319-CF |
| Alternate Names | 2-Thiolanimine hydrochloride; 2IT; Dihydro-2(3H)-thiophenimine hydrochloride; Trauts reagent |
| Application Notes | 2-Iminiothiolane hydrochloride is a thiolating reagent that is used in the preparation of disulfide and thioether linked conjugates, such as for protein crosslinking. It has a preference for primary amino groups and reacts at pH 7-10 to give amidine compounds which contain free sulhydryl groups. The amidine linkage preserves the original primary amine positive charge. A mechanistic study of the reaction of 2-iminothiolane with amino groups in peptides and proteins has been published. 2-Iminothiolane has also been utilized to prepare glycoprotein-antibody conjugates, streptavidin-antibody conjugates, and avidin-protein nanoparticle conjugates. |
| Base Catalog Number | 151319 |
| Beilstein Registry Number | 3620079 |
| CAS # | 4781-83-3 |
| Extinction Coefficient | EmM = 8.84 (0.1 M HCl)(Lit.) |
| Format | Powder |
| Molecular Formula | C4H7NS·HCl |
| Molecular Weight | 137.625 g/mol |
| Personal Protective Equipment | Eyeshields, Gloves, Respirator filter |
| Source | Synthetic |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| UV Visible Absorbance | λ max: 248 nm (Lit.) |
| brand | MP Bio |
|---|---|
| Pakage | 1x100mg, 1x500mg |
