[02150175-CF] CAS 27964-99-4 | Poly-D-lysine hydrobromide, Molecular Weight, 70,000-150,000 | MP bio
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02150175-CF | CAS 27964-99-4 | Poly-D-Lysine Hydrobromide, MW 70K–150K | MPBIO
Key Features and Details
- Synthetic amino acid that enhances cell adhesion to solid substrates
- Has additionally been shown to eliminate prion proteins from infected cells
| SKU | 02150175-CF |
| Application Notes | It is typically used as a coating substrate for culture dishes, slides, etc. It enhances electrostatic interaction between negatively charged ions of the cell membrane and the culture surface. Both the D- and L- form of the poly-lysine can be used as a coating substrate since poly-lysine is a nonspecific attachment factor for cells; however, certain cells can digest poly-lysine. In this case, poly-D-lysine should be used as the attachment factor so that the cells are not disrupted by excessive uptake of L-lysine.Other uses for poly-lysine have been reported as well:• Conjugation to methotrexate for increased drug transport.• Microencapsulation of islets.• Use in simple reproducible procedure for chromosomal preparations from a variety of tissues.• Immobilation of living cells in biocompatible semipermeable microcapsules.• In the preparation of polycationic beads.• Conjugation to albumin and horseradish peroxidase to enhance cellular uptake. |
| Base Catalog Number | 150175 |
| Biochemical Physiological Actions | Poly-D-lysine hydrobromide is a synthetic amino acid that enhances cell adhesion to solid substrates. It has additionally been shown to eliminate prion proteins from infected cells. |
| CAS # | 27964-99-4 |
| Personal Protective Equipment | Eyeshields, Gloves,respirator filter |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
