[02151884-CF] CAS 9008-97-3 | Phytohemagglutinin | MP bio
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02151884-CF | CAS 9008-97-3 | Phytohemagglutinin | MPBIO
Key Features and Details
Phytohemagglutinin
SKU | 02151884-CF |
Alternate Names | PHA |
Application Notes | In medicine PHA proteins are useful and are used as a mitogen to trigger T-lymphocytes cell division and to activate latent HIV-1 from human peripheral lymphocytes.The lectin has a number of effects on cell metabolism; it induces mitosis, and affects the cell membrane in regard to transport and permeability to proteins. It is used as positive control in ELIspot assay. |
Base Catalog Number | 151884 |
Biochemical Physiological Actions | PHA consists of two molecular species, an erythroagglutinin (PHA-E) which has low mitogenic activity and high erythroagglutinin activity, and leucoagglutinin (PHA-L) which has high mitogenic and leucoagglutinating activity, but very low erythroagglutinating activity. PHA-E is not blood group specific, but agglutination can be inhibited by certain oligosaccharides. PHA-P is the protein form of PHA prior to separation and purification of erythroagglutinin and leucoagglutinin. PHA-M is the mucoprotein form. Conjugates are prepared from the corresponding purified lectins. |
CAS # | 9008-97-3 |
EC Number | 232-718-7 |
Format | Off-white Lyophilized Powder |
Protein or Enzyme Type | Lectins |
RTECS Number | TJ3470000 |
Source | Red Kidney Beans (Phaseolus vulgaris) |
Specific Activity | Shows agglutination when tested with human red blood cells. |
Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |