[02154904-CF] CAS 14252-80-3 | Bupivacaine hydrochloride | MP bio
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02154904-CF | CAS 14252-80-3 | Bupivacaine hydrochloride | MPBIO
Key Features and Details
Bupivacaine Hydrochloride
| SKU | 02154904-CF |
| Alternate Names | 1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide |
| Application Notes | Bupivacaine is used as a long-acting local anesthetic. It is used mainly for infiltration and regional nerveblocks, but is not recommended for topical anesthesia. |
| Base Catalog Number | 154904 |
| Biochemical Physiological Actions | Bupivacaine is a sodium channel blocker, local anesthetic. It binds to the intracellular portion of sodium channels and blocks sodium influx into nerve cells, which prevents depolarization. Since pain transmitting nerve fibres tend to be thinner and either unmyelinated or lightly myelinated, the agent can diffuse more readily into them than into thicker and more heavily myelinated nerve fibres like touch, proprioception, etc. (Myelin is non-polar / lipophilic). It should be noted, however, that bupivacaine also blocks specific potassium channels, an effect contributing to resting membrane potential depolarization. |
| CAS # | 14252-80-3 |
| EC Number | 241-917-8 |
| Hazard Statements | H300-H310-H330 |
| Molecular Formula | C18H28N2O · HCl |
| Molecular Weight | 324.893 g/mol |
| Personal Protective Equipment | Eyeshields, Faceshields, full-face particle respirator, Gloves, respirator cartridge, respirator filter |
| RTECS Number | TK6125000 |
| Safety Symbol | GHS06 |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
