[02159346-CF] CAS 53123-88-9 | Rapamycin | MP bio
0 ₩
Brand: MP Bio
NSC226080; 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine; AY 22989; Sirolimus; Rapamune /
Rapamycin
... people are viewing this right now
02159346-CF | CAS 53123-88-9 | Rapamycin | MP bio
관련 문서 다운로드 (MSDS, COA, SPEC, Datasheet, Brochures, Manuals) :
Key features and details
Rapamycin
| SKU | 02159346-CF |
| Alternate Names | NSC226080; 23,27-Epoxy-3H-pyrido2,1-c |1,4 |oxaazacyclohentriacontine; AY 22989; Sirolimus; Rapamune |
| Application Notes | Rapamycin is unique in its ability to inhibit lymphokine induced cell proliferation at the G1 and S phase as well as an irreversible cellular arrest at the G1 phase in S. cerevisiae cells. It also exhibits selective signal blocking leading to the activation of p70/85 S6 kinase, which is potentially due to the inhibition of FRAP autophosphorylation or protein kinase activity. Angiogenesis inhibition is also exhibited, possibly through the inhibition of the Akt pathway. Induces autophagy in yeast and mammalian cell lines. |
| Base Catalog Number | 159346 |
| Biochemical Physiological Actions | Rapamycin binds to and inhibits the molecular target of rapamycin (mTOR). It forms a complex with FKBP12 that binds to and inhibits the molecular target of rapamycin (mTOR). Rapamycin is a potent immunosuppressant and has anticancer activity. |
| CAS # | 53123-88-9 |
| Extinction Coefficient | E1 %, 1 cm (maximum wavelength, 95% ethanol) is: 417 (267 nm); 541 (277 nm); 416 (288 nm)(Lit.) |
| Format | Powder |
| Hazard Statements | H317 |
| Melting Point | 183-185 deg C |
| Molecular Formula | C51H79NO13 |
| Molecular Weight | 914.187 g/mol |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| Purity | ≥98% |
| RTECS Number | VE6250000 |
| Solubility | Sol in ether, 관련 문서 다운로드 (MSDS, COA, SPEC, Datasheet, Brochures, Manuals) : |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| brand | MP Bio |
|---|---|
| Pakage | 1x100g, 1x1mg |
