[02190146-CF] CAS 69-53-4 | Ampicillin | MP bio
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02190146-CF | CAS 69-53-4 | Ampicillin | MPBIO
Key Features and Details
Ampicillin
| SKU | 02190146-CF |
| Alternate Names | D[-]-a-Aminobenzylpenicillin; 6-[D(-)-a-Aminophenylacetamido]penicillanic acid |
| Application Notes | Ampicillin is used to select bacteria cells with specific resistance during general microbiology studies. It is used to study antibiotic resistance and penetration limitations, the synergy between multiple antibiotics, certain bloodstream infections, and has been used to develop PCR assays to detect resistance genes in cerebrospinal fluid. |
| Base Catalog Number | 190146 |
| Beilstein Registry Number | 1090925 |
| Biochemical Physiological Actions | Ampicillin is a β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. |
| CAS # | 69-53-4 |
| EC Number | 200-709-7 |
| Format | White powder |
| Grade | Anhydrous |
| Hazard Statements | H315-H317-H319-H334-H335 |
| Melting Point | 388 to 392° F (decomposes) (NTP, 1992) |
| Molecular Formula | C16H19N3O4S |
| Molecular Weight | 349.405 g/mol |
| Personal Protective Equipment | Dust mask, Eyeshields, Faceshields, Gloves |
| pKa | pKa = 2.5 (-COOH) pKa = 7.3 (-NH2) at 25 °C |
| RTECS Number | XH8350000 |
| Safety Symbol | GHS07, GHS08 |
| Solubility | 1 to 10 mg/mL at 70° F (NTP, 1992) |
| Typical Working Concentration | 100 mg/liter for both gram positive and gram negative bacteria |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
