[02190147-CF] CAS 7177-48-2 | Ampicillin, trihydrate | MP bio
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Aminobenzylpenicillin trihydrate; alpha-Aminobenzylpenicillin trihydrate ;D[-]-α-Aminobenzylpenicillin; 6-[D(-)-α-Aminophenylacetamido]penicillanic acid /
Ampicillin Trihydrate
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02190147-CF | CAS 7177-48-2 | Ampicillin, trihydrate | MP bio
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Ampicillin Trihydrate
| SKU | 02190147-CF |
| Alternate Names | Aminobenzylpenicillin trihydrate; alpha-Aminobenzylpenicillin trihydrate ;D- |-α-Aminobenzylpenicillin; 6-D(-)-α-Aminophenylacetamido |penicillanic acid |
| Application Notes | Ampicillin Trihydrate is commonly used to select for ampicillin resistance in mutated and transformed cells. It is also described for the use of inhancing luminol chemiluminescence. |
| Base Catalog Number | 190147 |
| Beilstein Registry Number | 5399534 |
| Biochemical Physiological Actions | A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. |
| CAS # | 7177-48-2 |
| EC Number | 200-709-7 |
| Format | Powder |
| Hazard Statements | H315-H317-H319-H334-H335 |
| Melting Point | 388 to 392° F (decomposes) (NTP, 1992) |
| Molecular Formula | C16H19N3O4S·3H2O |
| Molecular Weight | 403.45 g/mol |
| Personal Protective Equipment | Dust mask, Eyeshields, Faceshields, Gloves |
| pKa | At 25 °C ,pKa = 2.5 (-COOH),pKa = 7.3 (-NH2) (Lit.) |
| RTECS Number | XH8425000 |
| Safety Symbol | GHS07, GHS08 |
| Solubility | 1 to 10 mg/mL at 70° F (NTP, 1992) |
| Sterilization of Solutions | Autoclaving solutions of ampicillin will destroy activity. Solutions can be sterilized by filtration (0.22 um filter) and stored frozen (-20 °C or below). Frozen solutions can be stored for up to 3 months. |
| Typical Working Concentration | 100 mg/liter for both gram positive and gram negative bacteria. It is typically stable in media at 37 °C for approximately 3 days. |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
| brand | MP Bio |
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