[02190245-CF] CAS 357-08-4 | Naloxone hydrochloride | MP bio
0 ₩
Brand: MP Bio
Naloxone Hydrochloride
... people are viewing this right now
02190245-CF | 357-08-4 | Naloxone hydrochloride | MP Bio
관련 문서 다운로드 (MSDS, COA, SPEC, Datasheet, Brochures, Manuals) :
Key features and details
Naloxone Hydrochloride
| SKU | 02190245-CF |
| Alternate Names | Narcan; EN-1530; (5α)-4,5-Epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-one hydrochloride; 17-allyl-4,5α- epoxy-3,14-dihydroxymorphinan-6-one hydrochloride; (-)-N-allyl-14- hydroxynordihydromorphinone; N-allylnoroxymorphone; |
| Application Notes | The role of naloxone (1 µM) and other opioids on apoptosis in several human cancer cell lines has been probed. Naloxone (10-100 µM) has been used to study proliferation and neurogenesis in cultured rat adult hippocampal progenitors. Naloxone has also been utilized to modulate the NMDA receptor activation capability of the µ-opioid receptor agonist DAMGO. |
| Base Catalog Number | 190245 |
| Beilstein Registry Number | 6260807 |
| Biochemical Physiological Actions | Naloxone has an extremely high affinity for μ-opioid receptors in the central nervous system. Naloxone is a μ-opioid receptor competitive antagonist, and its rapid blockade of those receptors often produces rapid onset of withdrawal symptoms. Naloxone also has an antagonist action, though with a lower affinity, at κ- and δ-opioid receptors. |
| CAS # | 357-08-4 |
| EC Number | 206-611-0 |
| Format | Crystalline powder |
| Hazard Statements | H315-H319-H335 |
| Molecular Formula | C19H21NO4 • HCl |
| Personal Protective Equipment | Dust mask, Eyeshields, Gloves |
| RTECS Number | QD2275000 |
| Safety Symbol | GHS07 |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
