[02190319-CF] CAS 75621-03-3 | CHAPS | MP bio
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02190319-CF | CAS 75621-03-3 | CHAPS | MPBIO
Key Features and Details
- Nondenaturing zwitterionic detergent for solubilizing membrane proteins and breaking protein-protein interactions
- For protein solubilization in non denaturing isoelectric focusing and 2-D electrophoresis
| SKU | 02190319-CF |
| Aggregation Number | 4-14 (0-0.1 M Na+) |
| Alternate Names | 3-[(3-Cholamidopropyl)-dimethylammonio]-1-propane sulfonate; N,N-Dimethyl-N-(3-sulfopropyl)-3-[[(3a,5b,7a,12a)-3,7,12-trihydroxy-24-oxocholan-24-yl] amino]-1-propanaminium inner salt |
| Application Notes | CHAPS is commonly used for protein solubilization in isoelectric focusing and two-dimensional electrophoresis especially for non-denaturing (without urea) isoelectric focusing. CHAPS has been shown to give excellent resolution of some subcellular preparations and plant proteins. Its small micellar molecular weight (6150) and high CMC (6-10 mM) allow it to be removed from samples by dialysis. Can be used as a non-toxic stabilizing agent for growth factors. |
| Base Catalog Number | 190319 |
| CAS # | 75621-03-3 |
| Critical Micelle Concentration | 6-10 mM |
| Hazard Statements | H315-H319-H335-H360D |
| Melting Point | 265°C (Lit.) |
| Molecular Formula | C32H58N2O7S |
| Molecular Weight | 614.9 |
| pH | 4.0 – 7.0 (10% aq soln) |
| Purity | ≥98% |
| Safety Symbol | GHS07, GHS08 |
| Solubility | Soluble in water (100 mg/mL – clear, colorless to slightly yellow solution). |
| Typical Working Concentration | Concentrations between 1-4% (v/v) are typically used in an isoelectric focusing gel. |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
