[02190679-CF] CAS 9028-86-8 | Aldehyde dehydrogenase | MP bio
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02190679-CF | CAS 9028-86-8 | Aldehyde dehydrogenase | MPBIO
Key Features and Details
- From yeast
| SKU | 02190679-CF |
| Alternate Names | Aldehyde:NAD[P]+ oxidoreductase; ALDH |
| Application Notes | Aldehyde dehydrogenase oxidizes a number of aliphatic and aromatic aldehydes. Acetyl-GSH is not hydrolyzed. |
| Base Catalog Number | 190679 |
| Biochemical Physiological Actions | Aldehyde dehydrogenase is a tetramer and has several different isoforms. The enzyme tested in 0.01 M pyrophosphate buffer shows a sharp optimum around pH 9.3 with acetaldehyde as substrate. Potassium ions and cysteine are essential for the enzyme’s activity. Rubidium or NH4+ can be substituted for K+, and glutathione for cysteine. Lithium, Na+, and Cs+ inhibit the reaction. Aldehyde dehydrogenase is inhibited by propylurea, crotonaldehyde, n-propyl isocyanate, cyclohexyl isocyanate, 1-n-propyl-1-[(4-chlorophenyl)sulphonyl]-3-n-propylurea, and 1-methyl-1-[(4-chlorophenyl)sulphonyl]-3-n-propylurea. The enzyme may be utilized to quantitate aldehydes present in blood. |
| CAS # | 9028-86-8 |
| EC Number | 232-845-3 |
| Extinction Coefficient | 9.4 (279 nm)(Lit) |
| Format | Freeze dried stabilized powder, Potassium Activated |
| Personal Protective Equipment | Eyeshields, Gloves, respirator filter |
| Source | Yeast |
| Specific Activity | Protein-~5 u/mg, solid-≥1 u/mg solid |
| Unit Definition | One unit causes the oxidation of one µ mole of acetaldehyde to acetic acid per minute at pH 8.0 and 25 °C in the presence of potassium ions and thiols. |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
