[02194679-CF] CAS 70-18-8 | Glutathione reduced, cell culture reagent, ≥98% | MP bio
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02194679-CF | CAS 70-18-8 | GSH, cell culture reagent, ≥98% (5g, MPBIO) | MPBIO
Key Features and Details
Glutathione Reduced
| SKU | 02194679-CF |
| Alternate Names | γ-L-Glutamyl-L-cysteinyl-glycine; GSH; ?-Glu-Cys-Gly |
| Application Notes | Glutathione suppresses human immunodeficiency virus expression in chronically infected monocytic cells. It is a useful tripeptide involved in many aspects of metabolism, including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. |
| Base Catalog Number | 194679 |
| Beilstein Registry Number | 1729812 |
| Biochemical Physiological Actions | Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents. |
| CAS # | 70-18-8 |
| EC Number | 200-725-4 |
| Format | Powder |
| Grade | Cell Culture Grade |
| Melting Point | 195 °C |
| Molecular Formula | H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H |
| Molecular Weight | 307.321 g/mol |
| Personal Protective Equipment | Eyeshields,Gloves,respirator filter |
| Purity | ≥98% |
| RTECS Number | MC0556000 |
| Solubility | 292.5 mg/mL |
| Typical Working Concentration | May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose. |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
