[02195489-CF] CAS 11140-99-1 | Ristocetin, sulfate salt | MP bio
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02195489-CF | CAS 11140-99-1 | Ristocetin, sulfate salt | MPBIO
Key Features and Details
Ristocetin Sulfate Salt
| SKU | 02195489-CF |
| Alternate Names | Ristomycin monosulfate |
| Application Notes | Ristocetin A has platelet aggregating activity and has been used in platelet aggregation studies. Studies have demonstrated that Ristocentin A dimerizes and creates two binding sites for cell wall peptides. |
| Base Catalog Number | 195489 |
| Biochemical Physiological Actions | Ristocetin activates platelets. Ristocetin-induced platelet agglutination (RIPA) is decreased in patients undergoing chronic hemodialysis. Together with increased plasma glycocalicin levels (a product of enzymatic cleavage of GPIb), RIPA may contribute to diminished platelet adhesion to vascular subendothelium and increased bleeding associated with uremia. Addition of ristocetin and vWf caused specific agglutination of rGPIbα-liposomes suporting the potential use of rGPIbα-liposomes to enhance platelet function in vivo and support hemostasis in thrombocytopenic individuals. |
| CAS # | 11140-99-1 |
| EC Number | 215-770-5 |
| Format | Powder |
| Molecular Formula | C95H110N8O44·H2SO4 |
| Molecular Weight | 2067.937 g/mol |
| Personal Protective Equipment | Eyeshields, Gloves, Respirator filter |
| Purity | ≥90% Ristocetin A |
| RTECS Number | VJ8580000 |
| Usage Statement | Unless specified otherwise, MP Biomedical’s products are for research or further manufacturing use only, not for direct human use. For more information, please contact our customer service department. |
