[A18236] CAS 90719-32-7 | (S)-(-)-4-Benzyl-2-oxazolidinone, 99%
0 ₩
90719-32-7 |
CAS : 90719-32-7
MDL : MFCD00064496
Chemical Properties
Formula : C10H11NO2
Formula weight : 177.20
Melting Point : 87-89°
Sensitivity : Hygroscopic. Ambient temperatures.
Form : Powder
Solubility : Insoluble in water.
Literature References
Evans chiral auxiliary; compare (4S)-(-)-Isopropyl-2-oxazolidinone, A14029. For details of use in enantioselective aldol condensation, see: Org. Synth. Coll., 8, 339 (1993): A simplified method of acylation of the oxazolidinone, avoiding the need for rigorously anhydrous conditions, has been reported using acyl chlorides, anhydrides or pivaloyl mixed anhydrides as the acylating agents catalyzed by DMAP: Synthesis, 1283 (1996). See also (4S)-(-)-Isopropyl-2-oxazolidinone, A14029.
Applications
(S)-(-)-4-Benzyl-2-oxazolidinone is used in chiral auxiliary asymmetric alkylation. It has been used in the synthesis of (S)-equol. Preparation and functionalization of chiral, stabilized ylides. It was used for asymmetric synthesis of (3R)- and (3S)-piperazic acid.
Grade Specifications
GHS Hazard and Precautionary Statements
Hazard Statements :
Precautionary Statements : Other References:Beilstein: 3649667
| Pakage | 1g, 25g, 5g |
|---|---|
| brand | Alfa Aesar |
