[A18742] CAS 7693-46-1 | 4-Nitrophenyl chloroformate, 97%

CAS : 7693-46-1
UN# : UN3261
MDL : MFCD00007321
Hazard Class : 8
EINECS : 231-706-9
Packing Group : II

Other name :

Chloroformic acid 4-nitrophenyl ester

Chemical Properties

Formula : C7H4ClNO4
Formula weight : 201.57
Melting Point : 75-82°
Boiling Point : 159-162°/19mm
Flash point : >110°(230°F)
Sensitivity : Keep Cold. Moisture Sensitive.
Form : Solid
Solubility : Soluble in acetone, chloroform, acetone, toluene and benzene.

Literature References

Reagent for protection of nucleoside alcohols. The carbonate derivatives readily undergo aqueous hydrolysis in the presence of imidazole: J. Org. Chem., 33, 3699 (1967). For use in the formation of a carbonate linker in an efficient N-terminal attachment methodology for solid phase peptide synthesis, see: Synlett, 1609 (2000).

Notes

Moisture sensitive. Store in a cool place. Incompatible with water, acids, alcohols, ammonia, amines and strong bases.Other References:Beilstein: 518127UN#: UN3261

Grade Specifications

Grade Specifications

Hazard Statements : H301-H332-H314-H318Toxic if swallowed.Harmful if inhaled.Causes severe skin burns and eye damage.Causes serious eye damage.
Precautionary Statements : P260-P301+P310-P303+P361+P353-P305+P351+P338-P405-P501aDo not breathe dust/fume/gas/mist/vapours/spray.IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.