[A18976] CAS 80-08-0 | 4,4′-Diaminodiphenyl sulfone, 98% | Alfa
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Brand: Alfa Aesar
80-08-0 | C12H12N2O2S | dapsone N’-diphenyl sulfondiamide N dapson-fatol diaphenylsulfone dds sulphonyldianiline sulfone ucb sulfanona-mae 4,4′-sulfonylbisbenzeneamine dumitone P,P-sulphonylbisbenzamine
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Chemical Identifiers
CAS
80-08-0
Molecular Weight (g/mol)
248.30
Synonym
dapsone N’-diphenyl sulfondiamide N dapson-fatol diaphenylsulfone dds sulphonyldianiline sulfone ucb sulfanona-mae 4,4′-sulfonylbisbenzeneamine dumitone P,P-sulphonylbisbenzamine
SMILES
NC1=CC=C(C=C1)S(=O)(=O)C1=CC=C(N)C=C1
InChI Key
MQJKPEGWNLWLTK-UHFFFAOYSA-N
Molecular Formula
C12H12N2O2S
IUPAC Name
4-(4-aminobenzenesulfonyl)aniline
Specifications
Appearance (Color)
White to pale cream
Form
Powder
Assay (HPLC)
≥97.5%
Identification (FTIR)
Conforms (non-U.S. specification)
Melting Point (clear melt)
175.0-181.0°C (non-U.S. specification)
설명
It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. It is a second-line medication for the treatment and prevention of Pneumocystis pneumonia and for the prevention of toxoplasmosis in those who have poor immune function. Additionally, it has been used for acne as well as other skin conditions. Moreover it is employed as an anti-inflammatory drug, anti-infective drug, a leprostatic drug and an antimalarial drug.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Insoluble in water. Solubility in hot methanol is almost transparent. Soluble in DMSO, ethanol and acetone.
Insoluble in water. Solubility in hot methanol is almost transparent. Soluble in DMSO, ethanol and acetone.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Other References:
Merck Index:14,2822Beilstein:788055
GHS Hazard and Precautionary Statements
Hazard Statements:H302-H373
GHS H StatementH302Harmful if swallowed.
Precautionary Statements:P260-P264b-P270-P301+P312-P314-P330-P501c
Risk & Safety
TSCA:YesRTECS Number:BY8925000
경고:RUO – Research Use Only
CAS80-08-0FORMULAC12H12N2O2SEINECS201-248-4MDLMFCD00007887
| Pakage | 100g, 500g |
|---|---|
| brand | Alfa Aesar |
