[B20010] CAS 57-66-9 | Probenecid, 98%

CAS : 57-66-9
MDL : MFCD00038402
EINECS : 200-344-3

Other name :

4-(Di-n-propylaminosulfonyl)benzoic acid4-(Di-n-propylsulfamoyl)benzoic acid

Chemical Properties

Formula : C13H19NO4S
Formula weight : 285.36
Melting Point : 198-199°
Sensitivity : Ambient temperatures.
Form : Powder
Solubility : Soluble in water (partly miscible), solutions of alkali hydroxides,, ethanol (100 mM), acetone, chloroform, sodium hydroxide (1 M), DMSO (100 mM), methanol, dilute acids (practically insoluble), dilute alkalies, and ether (slightly soluble).

Applications

It is a uricosuric drug, that is, it increases uric acid excretion in the urine. It is primarily used in treating gout and hyperuricemia. Probenecid was developed as an alternative to caronamide to competitively inhibit renal excretion of some drugs, thereby increasing their plasma concentration and prolonging their effects.

Grade Specifications

GHS Hazard and Precautionary Statements

Hazard Statements : H301-H315-H319-H335Toxic if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.
Precautionary Statements : P261-P301+P310-P305+P351+P338-P302+P352-P405-P501aAvoid breathing dust/fume/gas/mist/vapours/spray.IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF ON SKIN: Wash with plenty of soap and water.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References :

Merck : 14,7754