[J62200] CAS 17230-88-5 | Danazol

CAS : 17230-88-5
MDL : MFCD00056838
EINECS : 241-270-1

Other name :

17beta-Hydroxy-2,4,17a-pregnadien-20-yno[2,3-d]isoxazole2,4,17a-Pregnadien-20-yno[2,3-d]isoxazol-17-ol

Chemical Properties

Formula : C22H27NO2
Formula weight : 337.46
Melting Point : 218-220°
Sensitivity : Store at -20°C.
Form : Powder
Solubility : Partly soluble in water. Soluble in chloroform (25 mg/ml), acetone, acetonitrile, and ethanol. 17beta-Hydroxy-2,4,17a-pregnadien-20-yno[2,3-d]isoxazole and 2,4,17a-Pregnadien-20-yno[2,3-d]isoxazol-17-ol are the synonym of this compound.

Applications

Danazol is a synthetic gonadotropin inhibitor which has a preventive effect on estrogen -related endometrial carcinogenesis in mice. Danazol therapy has also shown regression of established mammary carcinoma in rats. This medication is used in women to treat pelvic pain and infertility due to a certain uterus disorder (endometriosis) and also to treat breast pain/tenderness/nodules due to a certain breast condition (fibrocystic breast disease). It is also used in both men and women to prevent swelling of the abdomen/arms/legs/face/airway due to a certain congenital disease

Grade Specifications

GHS Hazard and Precautionary Statements

Hazard Statements : H301-H311-H332-H361Toxic if swallowed.Toxic in contact with skin.Harmful if inhaled.Suspected of damaging fertility or the unborn child.
Precautionary Statements : P261-P301+P310-P361-P302+P352-P405-P501aAvoid breathing dust/fume/gas/mist/vapours/spray.IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.Remove/Take off immediately all contaminated clothing.IF ON SKIN: Wash with plenty of soap and water.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

Other References :

Merck : 14,2812