[J67241] CAS 67-66-3 | Chloroform, Molecular Biology Reagent | Alfa
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Brand: Alfa Aesar
67-66-3 | CHCl3 | chloroform caswell no. 192 C-H-cl3 methenyl chloride epa pesticide chemical code 020701 chloroform (substance) 1,1,1-trichloromethane trichloormethaan chloroform (product) chloroformium pro narcosi
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Chemical Identifiers
CAS
67-66-3
Molecular Weight (g/mol)
119.37
Synonym
chloroform caswell no. 192 C-H-cl3 methenyl chloride epa pesticide chemical code 020701 chloroform (substance) 1,1,1-trichloromethane trichloormethaan chloroform (product) chloroformium pro narcosi
SMILES
ClC(Cl)Cl
InChI Key
HEDRZPFGACZZDS-UHFFFAOYSA-N
Molecular Formula
CHCl3
IUPAC Name
trichloromethane
Specifications
Assay from Suppliers CofA
≥99.5%
Assay (special)
Lead (Pb): ≤0.00001% (≤0.1 ppm)
Water Content (Karl Fischer Titration)
≤0.02%
Appearance (Color)
Clear colorless
Form
Liquid
설명
Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.
Chloroform is a common laboratory reagent favored for use as a solvent due to the compounds relative unreactivity and miscibility with most organic compounds. Chloroform is also used in organic synthesis as a source for CCl2. In the swine tracheal smooth muscle, chloroform has been demonstrated to directly and in a concentration dependent manner induce contractions. It has been observed that Chloroform can release Ca2+ from ryanodine sensitive receptors in chloroform-induced contraction in swine tracheal smooth muscle. At concentrations of 100 and 250 ppm in mouse splenocyte, basal proliferation was increased yet a decrease in circulating neutrophils was documented.
Solubility
Soluble in water at 20°C 8 g/L.
Notes
Stabilized with approx. 50 ppm amylene
Other References:
Merck Index:14,2141UN Number:UN1888Beilstein:1731042
GHS Hazard and Precautionary Statements
Hazard Statements:H302-H315-H319-H331-H335-H336-H351-H361d-H373
GHS H StatementH351-H373-H302-H315 Suspected of causing cancer. May cause damage to organs through prolonged or repeated exposure. Harmful if swallowed. Causes skin irritation.
Precautionary Statements:P201-P202-P260-P264b-P270-P271-P280i-P281-P301+P312-P302+P352-P304+P340-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c
Risk & Safety
TSCA:YesRTECS Number:FS9100000
경고:RUO – Research Use Only
CAS67-66-3FORMULACHCl3HAZARD CLASS6.1EINECS200-663-8MDLMFCD00000826PACKAGING GROUPIII
| Pakage | 2.5L, 500ml, 1L |
|---|---|
| brand | Alfa Aesar |
