[L14197] CAS 50893-53-3 | 1-Chloroethyl chloroformate, 98%

CAS : 50893-53-3
UN# : UN2742
MDL : MFCD00000647
Hazard Class : 6.1
EINECS : 256-834-2
Packing Group : II

Other name :

Chloroformic acid 1-chloroethyl ester

Chemical Properties

Formula : C3H4Cl2O2
Formula weight : 142.97
Melting Point : -65°
Boiling Point : 119-121°
Flash point : 45°(113°F)
Density : 1.312
Refractive Index : 1.4230
Sensitivity : Keep Cold. Moisture Sensitive.
Solubility : Miscible with most organic solvents.

Literature References

Reagent, introduced by Olofson, and found to be superior to other chloroformates for dealkylation of tert-amines, e.g. N-alkylpiperidines to piperidines: J. Org. Chem., 49, 2081, 2795, 2081 (1984). For selective debenzylation of tert-amines, see: Synlett, 195 (1993). For reviews, see: Pure Appl. Chem., 60, 1715 (1988); Synthesis, 1 (1989).

Notes

Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agent, strong base, alcohols and amines.Other References:Beilstein: 1747601UN#: UN2742

Grade Specifications

Grade Specifications

Hazard Statements : H330-H302-H314-H318-H226Fatal if inhaled.Harmful if swallowed.Causes severe skin burns and eye damage.Causes serious eye damage.Flammable liquid and vapour.
Precautionary Statements : P210-P303+P361+P353-P304+P340-P305+P351+P338-P320-P330-P405-P501aKeep away from heat/sparks/open flames/hot surfaces. – No smoking.IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment is urgent (see label).Rinse mouth.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.